“We might have got our formation wrong … but we came back into it and showed great character,” Arsenal midfielder Jack Wilshere. “We showed our quality going forward.”Unlike Chelsea. A recovery rarely looked on the cards from Antonio Conte’s disjointed side in a derby that exposed the visitors’ shortages in the squad.Chelsea’s attacking threat was sapped by the loss of Willian in the first half with a hamstring problem, and Conte was forced to bring on Ross Barkley for his debut.The new recruit from Everton was lacking sharpness in his first match since being injured May. But Conte was forced to deploy the midfielder as a “false nine” at times. It was little wonder the goal threat was so lacking from a side that won the Premier League last season.Chelsea’s hopes of defending that title faded long ago, with Man City 15 points ahead of the third-place champions. Arsenal is languishing in sixth place but Wenger is still through to a fourth domestic final in five seasons.ADVERTISEMENT View comments 2 ‘newbie’ drug pushers fall in Lucena sting Kammuri turning to super typhoon less likely but possible — Pagasa For once, it’s not the FA Cup providing cover for Wenger. Arsenal’s defense of the more prestigious domestic cup ended at the first hurdle in an embarrassing loss to Nottingham Forest earlier this month. But a first trip to the League Cup final since 2011 gives Wenger a chance on Feb. 25 to add the only piece of domestic silverware missing in more than 21 years at Arsenal. Globe Business launches leading cloud-enabled and hardware-agnostic conferencing platform in PH Typhoon Kammuri accelerates, gains strength en route to PH Don’t miss out on the latest news and information. Read Next Arsenal’s Shkodran Mustafi controls the ball during the English League Cup semifinal second leg soccer match between Chelsea and Arsenal at the Emirates stadium in London, Wednesday, Jan.24, 2018. (AP Photo/Matt Dunham)LONDON — Two fortuitous goals helped Arsenal beat Chelsea 2-1 on Wednesday and seal a League Cup final meeting with Manchester City, providing a glimmer of joy in a gloomy domestic campaign.Both Arsenal goals received a helping hand from Chelsea defender Antonio Ruediger as the semifinal meeting of London rivals came to life after a sterile, scoreless first leg two weeks ago.ADVERTISEMENT MOST READ John Lloyd Cruz a dashing guest at Vhong Navarro’s wedding Trending Articles PLAY LIST 00:50Trending Articles00:59Sports venues to be ready in time for SEA Games01:27Filipino athletes get grand send-off ahead of SEA Games01:29Police teams find crossbows, bows in HK university01:35Panelo suggests discounted SEA Games tickets for students02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City Brace for potentially devastating typhoon approaching PH – NDRRMC LATEST STORIES Slow and steady hope for near-extinct Bangladesh tortoises Antetokounmpo says Kidd helped him grow into dominant player NEXT BLOCK ASIA 2.0 introduces GURUS AWARDS to recognize and reward industry influencers Chelsea raced into a seventh-minute lead through Eden Hazard but Arsenal quickly fought back. Nacho Monreal’s free header from a corner ricocheted off the heads of Chelsea duo Marcos Alonso and Ruediger before flying into the net in the 12th minute.Arsenal took the lead on the hour when Alexandre Lacazette’s cross was inadvertently diverted by Ruediger into the path of Granit Xhaka, who poked the ball past goalkeeper Willy Caballero.FEATURED STORIESSPORTSWATCH: Drones light up sky in final leg of SEA Games torch runSPORTSLillard, Anthony lead Blazers over ThunderSPORTSMalditas save PH from shutout“In the first half we gave them too much respect, maybe, and we suffered from that,” Arsenal manager Arsene Wenger said. “In the second half we rectified that.”In part thanks to Wenger’s shift to a three-man defense in the second half.
Source:ERA-EDTA There are relatively few treatments that have been shown to slow progression of CKD. As nephrologist, we have used sodium bicarbonate to correct metabolic acidosis in people with CKD for some time, but definite evidence of benefit has been lacking. Our study shows that this very cost-effective treatment is safe and improves kidney and patient survival,”Lead investigator Dr Antonio Bellasi Reviewed by James Ives, M.Psych. (Editor)Jun 17 2019Defined as serum bicarbonate less than 22 mmol/L, metabolic acidosis is common in people with CKD stages 4-5 (eGFR < 30 ml/min/1.73 m2) and is directly related to worsening kidney function. Metabolic acidosis is a problem because it is associated with complications such as bone disease, muscle wasting, high levels of blood potassium (hyperkalemia), insulin resistance, high cholesterol (hyperlipidemia), and with a more rapid decline in kidney function--shown by rising blood creatinine--and increased risk of death.International guidelines recommend that, when serum bicarbonate concentration falls below 22 mmol/l, CKD patients should be treated with oral sodium bicarbonate to maintain serum bicarbonate within the normal range, unless contraindicated. However, until recently, very few studies have tested the effectiveness of bicarbonate therapy in improving metabolic acidosis or its potential benefits in patients with CKD.Related StoriesOne-fifth of U.S. surgeons still 'overusing' riskier method to create kidney dialysis access, study findsLow dose of endotoxin could have protective effect on men at risk of acute kidney injuryNew imaging probe allows earlier detection of acute kidney failureResults of the UBI trial announced for the first time during the ERA-EDTA Congress in Budapest, now provide strong evidence for the benefits of correcting metabolic acidosis with sodium bicarbonate in people with late-stage CKD.The prospective, open-label, randomized controlled trial assigned 740 patients with CKD-3b and CKD stage 4 to either sodium bicarbonate (376 patients) or standard care without sodium bicarbonate (364 patients). The patients had a mean age of 67.8 years, creatinine clearance 30 ml/min, and serum bicarbonate 21.5 mmol/l. At the end of three years, doubling of creatinine occurred in significantly fewer patients randomized to sodium bicarbonate: 6.6% versus 17.0% receiving standard care, p<0.001. This translates into a relative risk reduction of 64% in kidney disease progression (hazard ratio [HR] 0.36; 95% confidence interval [CI] 0.22-0.58; p<0.001).Similarly, the likelihood of starting RRT was also significantly lower in the sodium bicarbonate group. At the end of the study, 6.9% of patients receiving sodium bicarbonate had started RRT compared to 12.3% of the standard care group--a relative risk reduction of 50% (p=0.004; HR: 0.5; 95% CI: 0.31-0.81; p=0.005). The risk of death was also significantly lower among sodium bicarbonate-treated patients at 3.1% compared to 6.8 % of the standard care group--a relative risk reduction of 57% (p=0.004; HR 0.43; 95%CI 0.22-0.87; p=0.01). Treatment with sodium bicarbonate was well tolerated, with no significant effects on blood pressure, total body weight or hospitalizations.
Headbutting Tiny Worms Are Really, Really LoudThis rapid strike produces a loud ‘pop’ comparable to those made by snapping shrimps, one of the most intense biological sounds measured at sea.Volume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Better Bug Sprays?01:33 facebook twitter 发邮件 reddit 链接https://www.livescience.com/65945-tiny-worms-emit-loud-noise.html?jwsource=cl已复制直播00:0000:3500:35Your Recommended Playlist01:33Better Bug Sprays?01:08Why Do French Fries Taste So Bad When They’re Cold?04:24Sperm Whale Befriends Underwater Robot00:29Robot Jumps Like a Grasshopper, Rolls Like a Ball02:31Surgical Robotics00:29Video – Giggly Robot关闭 Tiny, feisty worms that live off the coast of Japan fight by headbutting each other — and they aren’t quiet about it. During these feuds, the worms emit one of the loudest sounds in the ocean, according to a new study. The source of the underwater hullabaloo is a nearly transparent segmented worm called the Leocratides kimuraorum, which lives inside sponges 279 to 554 feet (85 to 169 meters) deep off the coast of Japan. [The 12 Weirdest Animal Discoveries]Advertisement These wigglies are just a tad more than an inch (29 millimeters) long and have lengthy tentacles and a big mouth (literally). These seemingly quiet creatures revealed their true nature under the spotlight in the lab. A group of researchers used an instrument called a hydrophone to record 15 pops that were emitted from three kimuraorums as they were fighting. In a marine feud researchers dub “mouth-fighting,” the worms approached each other headfirst with their mouths open. During such encounters, the worms’ pharynx muscles expand rapidly, creating a cavitation bubble that collapses and produces a loud “pop” while the worms launch into each other. The researchers found that these pops can reach 157 decibels in the water (which is a different measurement than decibels in the air). From right next to the water tank, the pops sounded like humans snapping their fingers, lead author Goto Ryutaro, an assitant professor at Kyoto University told Live Science. “Though they probably sound louder if you hear them in the water.” The worms are as loud as snapping shrimps, which are one of the biggest noisemakers in the ocean, the authors wrote. What’s more, they found that these worms did not make any noise when simply disturbed, they only did so when they were fighting. They “may use mouth-fighting to defend territory or living chambers from other worms,” the authors wrote July 8 in the journal Current Biology. “A loud pop may be a byproduct of the rapid mouth attack, but it may also aid intraspecific communication.” A loud noise could somehow determine the victor of the fight or even reveal the whereabouts of nearby worms, they wrote. Strange Love: 10 Animals with Truly Weird Courtship Rituals The 10 Strangest Animal Discoveries 13 Extremely Weird Animal Feet Originally published on Live Science.by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeVikings: Free Online GamePlay this for 1 min and see why everyone is addicted!Vikings: Free Online GameUndoTruthFinder People Search SubscriptionOne Thing All Liars Have in Common, Brace YourselfTruthFinder People Search SubscriptionUndoKelley Blue Book2019 Lexus Vehicles Worth Buying for Their Resale ValueKelley Blue BookUndoGundry MD Total Restore SupplementU.S. Cardiologist: It’s Like a Pressure Wash for Your InsidesGundry MD Total Restore SupplementUndoArticles VallyDad Cuts Daughter’s Hair Off For Getting Birthday Highlights, Then Mom Does The UnthinkableArticles VallyUndoNucificTop Dr. Reveals The 1 Nutrient Your Gut Must HaveNucificUndo